The research group “Epigenetics, Metabolism and Longevity ” of the FBN is seeking a highly motivated
DFG funded PhD student position (m/f/d) for 36 months starting as soon as possible
Reference number: 2021-03 Task Description: The Peleg Laboratory of epigenetics, metabolism and longevity at the FBN, Dummerstorf, is now recruiting a PhD student to join our team. Part of the project will also take place in Munich, Germany.
We are focused on understanding metabolic and epigenetic changes that occur in response to environmental stress and early aging. Our lab combines model organism work (flies and mice) with various techniques including mass spectrometry, molecular biochemistry and behavioral testing. We are currently exploring novel alterations in the metabolic- epigenetic axis in response to combined stress conditions. Specifically, we are interested in regulation of acetyl-CoA metabolism and histone acetylation in response to low food availability.
We welcome applications from excellent, highly-motivated candidates who enjoy collaborating with fellow scientists to advance our understanding on epigenetic response to stress.
Requirements: 1.Must hold or will shortly receive a master’s degree in Biology, Medicine, or a relevant Biological/Biochemical discipline 2. Able to work independently 3. Passionate about scientific integrity 4. Motivated to study metabolism and epigenetic 5. Experience in fly work and basic data analysis in R will be an advantage
We offer Multifaceted and challenging research tasks in a performance‐oriented and family‐friendly environment Modern equipment and integration in international and national research projects Employment conditions according to the provisions of Tarifvertrag für den öffentlichen Dienst der Länder (TV-L), remuneration at the level of 65% of salary grade 13 TV-L Participation in the company pension scheme (VBL) Assistance with formal issues while settling into the new living environment
Masters students in metabolism – epigenetics during aging
The newly established Peleg Laboratory of epigenetics, metabolism and longevity at the FBN, Dummerstorf, is now recruiting 1-2 masters students to join our team. We are focused on understanding the molecular changes that occur during early aging that determine healthy lifespan. Our lab combines model organism work (mice and flies) with various techniques, including mass spectrometry, molecular biochemistry, and behavioral testing. We are currently exploring novel modeling methods of aging to discover innovative therapy avenues, with the goal of preventing fitness decline and cognitive impairment.
We welcome applications from excellent, highly motivated candidates who enjoy collaborating with fellow scientists to advance our understanding of the molecular mechanisms of aging.
In particular, we seek student to join one of these two projects:
1. Characterizing altered metabolism - epigenetic connectivity in Titan mice. These mice were selected for 45 years based on their weight. As such, they are world-wide unique and exist only at the FBN. Strikingly, they are 3 times the size of a normal mouse, making them the biggest mouse model that exists. Furthermore, they display rapid aging process.
2. Protein acetylation regulation of metabolic activity and response to stress in Drosophila. In this project we will aim to better understand how acetylation of non-histone protein regulate metabolic activity and response to severe starvation in flies.
Please submit your CV and a short cover letter stating why you are interested in joining our lab. Applicants are required to speak English in the lab. Short listed candidates will be selected for an interview. The starting date is flexible. All application materials must be submitted in PDF format to Dr. Shahaf Peleg at firstname.lastname@example.org or email@example.com via our website www.peleglab-aging.com.